Dyadic Announces Analysis, License and Collaboration Agreement with Janssen for the Manufacture of Therapeutic Protein Candidates making use of its C1 System

JUPITER, Fla., Dec. 17, 2021 (World NEWSWIRE) — Dyadic Global, Inc. (“Dyadic”, “we”, “us”, “our”, or the “Company”) (NASDAQ: DYAI), a world biotechnology firm concentrated on even more improving upon, making use of, and deploying its proprietary C1-mobile protein output system to accelerate development, decrease manufacturing costs and increase the effectiveness of protein dependent vaccines and therapeutics, introduced that it has entered into a Exploration, License and Collaboration Agreement (“Agreement”) with Janssen Biotech, Inc. (‘’Janssen”), one of the Janssen Pharmaceutical Organizations of Johnson & Johnson. The Agreement was facilitated by Johnson & Johnson Innovation.

Underneath the conditions of the Settlement:

  • Janssen will shell out Dyadic an upfront payment of $500,000 for non-special rights to make the most of the C1 platform to establish C1 output cell strains for the production of Janssen’s therapeutic protein candidates versus many biologic targets.

  • Janssen will present R&D funding up to €1.6 million to establish and assess C1 creation mobile strains for its item candidates.

  • Janssen has the option to pay out a mid-7 determine payment for an exclusive license from Dyadic to use the C1 platform for the production of therapeutic proteins directed to a person precise focus on.

  • Even more, Janssen has an selection to obtain the following legal rights from Dyadic.

    • Upon exercise of the option, Dyadic would receive a milestone payment in the mid-7 figures and Janssen would have the ideal to include extra non-exceptional targets to the collaboration.

    • Dyadic would finish C1 platform engineering transfer, absolutely enabling Janssen to internally create C1 mobile strains against certified targets upon productive completion of know-how transfer, Dyadic is suitable to obtain a milestone payment in the very low seven figures.

  • For every single product or service prospect, Dyadic could obtain progress and regulatory milestones in the mid-7 figures.

  • Dyadic could receive industrial milestone payments in the lower nine figures for each solution, matter to a limit on the amount of this kind of goods. The sum will rely on the cumulative total of energetic pharmaceutical component made by Janssen for each and every merchandise manufactured with Dyadic’s C1 system.

“We are psyched to announce this strategic partnership with Janssen working with our C1-mobile protein manufacturing system. We carry on to develop our partnerships across a increasing range of therapeutic locations, and we carry on to think in the wide utility of Dyadic’s C1 technologies,” stated Mark Emalfarb, Dyadic’s President and Main Executive Officer.

About Dyadic International, Inc.

Dyadic Worldwide, Inc. is a international biotechnology firm which is creating what it thinks will be a most likely considerable biopharmaceutical gene expression system based mostly on the fungus Thermothelomyces heterothallica (formerly Myceliophthora thermophila), named C1. The C1 microorganism, which permits the enhancement and large-scale manufacture of reduced-cost proteins, has the possible to be more formulated into a secure and successful expression method that may support velocity up the progress, reduced manufacturing fees and enhance the functionality of biologic vaccines and medicine at adaptable industrial scales. Dyadic is making use of the C1 engineering and other technologies to carry out research, development and professional activities for the advancement and producing of human and animal vaccines and medicine, this kind of as virus like particles (VLPs) and antigens, monoclonal antibodies, Fab antibody fragments, Fc-Fusion proteins, biosimilars and/or biobetters, and other therapeutic proteins. Specified other exploration functions are ongoing which include things like the exploration of utilizing C1 to acquire and create specified metabolites and other biologic items. Dyadic pursues investigation and development collaborations, licensing arrangements and other industrial chances with its partners and collaborators to leverage the price and gains of these technologies in improvement and manufacture of biopharmaceuticals. As the getting older population grows in developed and undeveloped countries, Dyadic thinks the C1 technology might support provide biologic vaccines, medicine, and other biologic solutions to market place a lot quicker, in greater volumes, at reduced price tag, and with new properties to drug builders and manufacturers, and make improvements to entry and price tag to patients and the health care technique, but most importantly help save life.

Make sure you visit Dyadic’s web-site at http://www.dyadic.com for more information, together with particulars with regards to Dyadic’s options for its biopharmaceutical enterprise.

Risk-free Harbor About Forward-Looking Statements

This press launch has forward-hunting statements within just the which means of Part 27A of the Securities Act of 1933 and Area 21E of the Securities Trade Act of 1934, like people about Dyadic International’s anticipations, intentions, strategies, and beliefs pertaining to potential gatherings or long run monetary general performance. Actual situations or outcomes may perhaps vary materially from these in the ahead-wanting statements due to the fact of several vital factors, like those people explained in the Company’s most the latest filings with the SEC. Dyadic assumes no obligation to update publicly any these types of forward-on the lookout statements, whether or not because of new information and facts, foreseeable future activities or otherwise. For a more entire description of the hazards that could induce our precise benefits to vary from our existing anticipations, please see the segment entitled “Risk Factors” in Dyadic’s yearly studies on Form 10-K and quarterly studies on Form 10-Q submitted with the SEC, as these kinds of aspects may possibly be current from time to time in Dyadic’s periodic filings with the SEC, which are available on the SEC’s site and at http://www.dyadic.com.

Speak to:

Dyadic Intercontinental, Inc.
Ping W. Rawson
Main Monetary Officer
Phone: (561) 743-8333
E mail: [email protected]