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Presentation During New Developments in the Management of Pancreatic Cancer Study course Highlights Intra-Arterial Chemotherapy as a Likely Revolutionary Therapy for Pancreatic Cancer

RenovoRx Phase 3 TIGeR-PaC Medical Demo Preliminary Pharmacokinetic Information Featured

MIAMI & LOS ALTOS, Calif., November 09, 2021–(Organization WIRE)–RenovoRx, Inc. (Nasdaq: RNXT), a biopharmaceutical organization and innovator in targeted most cancers therapy, nowadays declared its novel therapy platform, RenovoTAMPTM (RenovoRx Trans-Arterial Micro-Perfusion), will be highlighted during a presentation by skilled panelist, Dr. Ripal Gandhi, at the Miami Most cancers Institute’s New Developments in the Administration of Pancreatic Cancer CME program this night.

Dr. Gandhi, a Principal Investigator in RenovoRx’s ongoing Phase 3 TIGeR-PaC research, and Professor of Interventional Radiology at the Miami Cancer Institute and Miami Cardiac and Vascular Institute, Florida Global University Herbert Wertheim School of Medicine, will explain the success from first medical studies of RenovoTAMP utilized in blend with radiation remedy and its added benefits when managing sufferers with phase 3 domestically highly developed pancreatic cancer (LAPC). He will also review the vital phases of the TIGeR-PaC protocol which works by using RenovoTAMP for the intra-arterial supply of gemcitabine, an authorized chemotherapeutic agent, to treat unresectable LAPC. To highlight a important variance concerning intravenous (IV) and intra-arterial (IA) chemotherapy, Dr. Gandhi will existing pharmacokinetic details, or facts describing the drug absorption/distribution/fat burning capacity/excretion of gemcitabine from 5 individuals in the Stage 3 TIGeR-PaC research that received intra-arterial gemcitabine. The facts demonstrates an somewhere around two-thirds reduction in systemic gemcitabine when in contrast to systemic degrees in clients historically getting IV infusion of gemcitabine.

“This progressive remedy system is enabling the qualified treatment method of inoperable LAPC with decreased aspect consequences standard of systemic chemotherapy, whilst shifting the focus to what is most essential to our sufferers: increasing good quality of lifetime and allowing for them to commit extra time with their spouse and children and liked types,” reported Dr. Gandhi. “RenovoTAMP, when made use of in combination with radiation treatment, is built to lessen arterial microvasculature, thereby minimizing leakage during drug shipping and delivery and maximizing drug supply right to the tumor.”

A duplicate and recording of Dr. Gandhi’s presentation, titled “Potential Upcoming Progressive Method for Pancreatic Most cancers: Intra-Arterial Chemotherapy,” will be accessible on RenovoRx’s website at https://renovorx.com.

About the Period 3 TIGeR-PaC Medical Demo

The TIGeR-PaC scientific trial is a randomized multi-center research applying the RenovoTAMPTM platform to evaluate RenovoRx’s 1st solution prospect, RenovoGemTM to treat unresectable LAPC as a result of the intra-arterial supply of gemcitabine, an permitted chemotherapeutic agent. TIGeR-PaC is currently enrolling regionally state-of-the-art, unresectable pancreatic cancer individuals. To learn far more about the review and the collaborating clinical demo web sites, visit https://renovorx.com/medical-trial/.

About RenovoRx, Inc.

RenovoRx is a medical-stage biopharmaceutical enterprise concentrated on battling most cancers by way of the localized remedy of tough to take care of tumors via its proprietary RenovoRx Trans-Arterial Micro-Perfusion (RenovoTAMPTM) treatment system. RenovoTAMP provides approved smaller molecule chemotherapeutic agents domestically to the good tumors. RenovoRx’s guide product or service prospect, RenovoGemTM, uses intra-arterial shipping and delivery of gemcitabine, an authorized chemotherapeutic agent, to treat unresectable locally state-of-the-art pancreatic cancer (LAPC) and is presently currently being analyzed in the Period 3 TIGeR-PaC demo for the therapy of LAPC.

RenovoRx’s patent portfolio involves seven U.S. patents for its know-how. RenovoRx has been granted Orphan Drug Designation for intra-arterial shipping and delivery of gemcitabine for the therapy of both pancreatic most cancers and bile duct most cancers.

RenovoRx received the Drug Delivery Technologies group of the Intense Innovation Awards – Daily life Sciences Edition 2020 for its RenovoTAMP technological know-how.

Understand far more by traveling to the RenovoRx web site or pursuing us on Facebook, LinkedIn and Twitter.

Forward-seeking statements

This press release is made up of forward-wanting statements within just the which means of Portion 27A of the Securities Act of 1933, and Part 21E of the Securities Exchange Act of 1934, including but not confined to statements regarding our Stage 1 (RR1) and Observational Registry (RR2) scientific tests, statements concerning the opportunity of RenovoTAMPTM, RenovoCath® or RenovoGemTM or concerning our ongoing TIGeR-PaC Section 3 clinical demo in LAPC, and statements about the possible for our solution candidates to deal with or provide clinically meaningful results for specified health care situations or health conditions. Statements that are not purely historical are ahead-searching statements. The ahead-wanting statements contained herein are based mostly upon our latest anticipations and beliefs with regards to foreseeable future activities, several of which, by their character, are inherently unsure, exterior of our command and entail assumptions that may possibly never ever materialize or may possibly verify to be incorrect. These could involve estimates, projections and statements relating to our research and advancement strategies, clinical trials, treatment system, company designs, objectives and envisioned working effects, which are based on latest anticipations and assumptions that are matter to known and unidentified dangers and uncertainties that may possibly induce true effects to vary materially from all those expressed or implied by these forward-hunting statements. These statements might be determined utilizing terms these kinds of as “may perhaps,” “expects,” “programs,” “aims,” “anticipates,” “believes,” “forecasts,” “estimates,” “intends,” and “likely,” or the destructive of these phrases or other comparable terminology about RenovoRx’s expectations system, designs or intentions, though not all ahead-hunting statements consist of these words. These ahead-looking statements are subject to a quantity of dangers, uncertainties and assumptions, that could cause actual activities to differ materially from those projected or indicated by this sort of statements, together with, amongst other issues: the timing of the initiation, development and potential effects of our preclinical studies, scientific trials and our investigate courses our potential to use and expand our treatment platform to develop a pipeline of item candidates our means to progress solution candidates into, and successfully complete, clinical trials the timing or chance of regulatory filings and approvals our estimates of the selection of patients who suffer from the health conditions we are targeting and the quantity of sufferers that may enroll in our scientific trials the commercialization likely of our product or service candidates, if approved our capacity and the probable to efficiently manufacture and provide our item candidates for scientific trials and for industrial use, if authorised long run strategic preparations and/or collaborations and the probable advantages of these types of arrangements our estimates with regards to expenditures, upcoming profits, capital needs and wants for more funding and our capacity to receive supplemental money the sufficiency of our existing hard cash and income equivalents to fund our long term working expenses and funds expenditure demands our ability to keep the ongoing services of our important personnel and to identify, employ and retain additional capable staff the implementation of our strategic options for our company and solution candidates the scope of security we are able to create and keep for mental property rights, such as our treatment system, merchandise candidates and exploration plans our capacity to deal with 3rd-get together suppliers and producers and their potential to conduct adequately the pricing, coverage and reimbursement of our product candidates, if accredited developments relating to our rivals and our marketplace, which include competing product or service candidates and therapies damaging impacts of the COVID-19 pandemic on our operations and other pitfalls.

Details concerning the foregoing and additional hazards may perhaps be observed in the segment entitled “Threat Components” in paperwork that RenovoRx information from time to time with the Securities and Exchange Fee.

Ahead-searching statements included herein are manufactured as of the day hereof, and RenovoRx does not undertake any obligation to update publicly this kind of ahead-on the lookout statements to replicate subsequent situations or circumstances, apart from as essential by law.

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Contacts

Chris Lehman, (650) 284-4433